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Viral load of human bocavirus-1 in stools from children with viral diarrhoea in Paraguay

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dc.contributor.author Proenca Modena, Jóse Luis
dc.contributor.author Martínez, Magaly
dc.contributor.author Amarilla, Alberto Anastacio
dc.contributor.author Espínola, Emilio E.
dc.contributor.author Galeano, María E.
dc.contributor.author Fariña, Norma
dc.contributor.author Russomando, Graciela
dc.contributor.author Aquino, Víctor H.
dc.contributor.author Parra, Gabriel
dc.contributor.author Arruda, Eurico
dc.date.accessioned 2019-12-21T19:56:51Z
dc.date.available 2019-12-21T19:56:51Z
dc.date.issued 2013
dc.identifier.issn 2576–2580
dc.identifier.uri http://dspace.conacyt.gov.py/xmlui/handle/123456789/42385
dc.description.abstract Since their discovery, four species of human bocavirus (HBoV) have been described in patients with respiratory and gastrointestinal diseases. However, a clear causal association between HBoV-1 and gastroenteritis has not been demonstrated. In this study, we describe the detection and quantification of HBoV-1 in stools from children with acute non-bacterial gastroenteritis using quantitative polymerase chain reaction. HBoV-1 genome was detected in 10.6% of stools with frequent association with rotavirus and norovirus. The median of HBoV-1 viral load was 1.88 × 104 genome/ml, lower than previously shown in secretions of patients with respiratory infections, without any obvious association between high viral load and presence of HBoV as single agent. Thus, although HBoV-1 was frequently detected in these patients, there is no clear causal association of this agent with diarrhoea. Indeed, HBoV-1 DNA in stools of patients with gastroenteritis without respiratory symptoms may be a remnant of previous infections or associated with prolonged shedding of virus in the respiratory or digestive tracts.
dc.format application/pdf
dc.language Inglés
dc.publisher Cambridge University Press
dc.relation.uri http://dspace.conacyt.gov.py/jspui/bitstream/123456789/42385/1/2013 viral load of human bocavirus-1 in stools from children with viral diarrhoea in paraguay.pdf
dc.source Epidemiology and Infection
dc.subject.mesh Viral load
dc.subject.mesh Diarrhea
dc.subject.mesh Feces
dc.subject.mesh Human bocavirus
dc.subject.mesh Virus diseases
dc.subject.mesh Polymerase chain reaction
dc.title Viral load of human bocavirus-1 in stools from children with viral diarrhoea in Paraguay
dc.type Artículo
dcterms.bibliographicCitation Epidemiology and Infection 141(12), 2576 - 2580. 2013
dc.contributor.identifier 2190440
dc.contributor.identifier 1439381
dc.contributor.identifier 1682813
dc.contributor.identifier 721952
dc.contributor.identifier 562072
dc.contributor.identifier 608027
dc.directorio.catalogador mgt
dc.identifier.doi 10.1017/S095026881300023X
dc.source.pages 2576 - 2580
dc.source.volume 141
dc.source.volume 12

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